Leucomycin A13
Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay.
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- CAS. Nr.: 78897-52-6
- Formel: C41H69NO14
- Molecular Weight:799.98
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 78897-52-6
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Molecular Weight 799.98
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Formel C41H69NO14
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SMILES
O=CC[C@@H](C[C@H]([C@H](/C=C/C=C/C[C@H]1C)O)C)[C@@H]([C@H]([C@@H](CC(O1)=O)O)OC)O[C@H](O[C@@H]2C)[C@@H]([C@H]([C@@H]2O[C@H](O[C@H]3C)C[C@@](O)([C@H]3OC(CCCCC)=O)C)N(C)C)O
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Synonyms
Kitasamycin A13
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)