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Litifilimab

(Synonyms: BIIB059)
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Based on 1 Customer Validation

Litifilimab (BIIB059) is a humanized IgG1 monoclonal antibody targeting BDCA2. Litifilimab induces internalization of BDCA2 receptors on the membrane of plasmacytoid dendritic cells, inhibits the TLR7/TLR9 signaling pathway, and suppresses the production of type I interferons. Litifilimab can be used in the research of systemic and cutaneous lupus erythematosus.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 99.51%
  • CAS. Nr.: 2407378-48-5
  • Molecular Weight:146.6 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Litifilimab
  • Experimental Validation Results for Litifilimab
  • Litifilimab Chemical Structure
    Litifilimab Chemical Structure
CAS. Nr.: 2407378-48-5
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Litifilimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

Alle Toll-like Receptor (TLR) Isoform-spezifische Produkte anzeigen

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CLEC4C Protein, Human can bind Litifilimab. The EC50 for this effect is 19.73 ng/mL.

  • Litifilimab Chemical Structure
    1/16
  • Litifilimab
  • Immobilized CLEC4C Protein, Human can bind Litifilimab. The EC50 for this effect is 19.73 ng/mL.