trans-4-Methylcyclohexanamine
Based on 1 Customer Validation
trans-4-Methylcyclohexanamine is an organic amine compound that can be used in the development of T. cruzi enzyme inhibitors.
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- Reinheit: 99.27%
- CAS. Nr.: 2523-55-9
- Formel: C7H15N
- Molecular Weight:113.20
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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Trypanosoma |
Enzyme inhibitors targeting Trypanosoma cruzi (the pathogen causing Chagas disease) represent a core area of current antiparasitic drug research and development.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2523-55-9
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Appearance Liquid (Density: 0.85 g/cm3)
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Molecular Weight 113.20
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Formel C7H15N
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Color Colorless to light yellow
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SMILES
N[C@H]1CC[C@H](C)CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (883.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (22.08 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (22.08 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (629 KB)
- English - EN (629 KB)
- Français - FR (629 KB)
- Deutsch - DE (629 KB)
- Norwegian - NO (629 KB)
- Español - ES (629 KB)
- Swedish - SV (629 KB)
- Italian - IT (629 KB)
- Korean - KR (629 KB)
- Portuguese - PT (629 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.8339 mL | 44.1696 mL | 88.3392 mL | 220.8481 mL |
| 5 mM | 1.7668 mL | 8.8339 mL | 17.6678 mL | 44.1696 mL | |
| 10 mM | 0.8834 mL | 4.4170 mL | 8.8339 mL | 22.0848 mL | |
| 15 mM | 0.5889 mL | 2.9446 mL | 5.8893 mL | 14.7232 mL | |
| 20 mM | 0.4417 mL | 2.2085 mL | 4.4170 mL | 11.0424 mL | |
| 25 mM | 0.3534 mL | 1.7668 mL | 3.5336 mL | 8.8339 mL | |
| 30 mM | 0.2945 mL | 1.4723 mL | 2.9446 mL | 7.3616 mL | |
| 40 mM | 0.2208 mL | 1.1042 mL | 2.2085 mL | 5.5212 mL | |
| 50 mM | 0.1767 mL | 0.8834 mL | 1.7668 mL | 4.4170 mL | |
| 60 mM | 0.1472 mL | 0.7362 mL | 1.4723 mL | 3.6808 mL | |
| 80 mM | 0.1104 mL | 0.5521 mL | 1.1042 mL | 2.7606 mL | |
| 100 mM | 0.0883 mL | 0.4417 mL | 0.8834 mL | 2.2085 mL |
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