Luzopeptin A
Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively.
For research use only. We do not sell to patients.
- CAS No.: 75580-37-9
- Formula: C64H78N14O24
- Molecular Weight:1427.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
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HIV-1 RT 7 nM (IC50) |
HIV-2 RT 68 nM (IC50) |
Chemical Information
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CAS No. 75580-37-9
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Molecular Weight 1427.38
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Formula C64H78N14O24
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SMILES
O=C1N2[C@@](C(NCC(N(CC(N([C@H](C(OC[C@H](C(N3[C@]([C@H](CC=N3)OC(C)=O)([H])C(NCC(N(CC(N([C@H](C(OC[C@H]1NC(C4=NC5=C(C=C(C=C5)OC)C=C4O)=O)=O)C(C)(O)C)C)=O)C)=O)=O)=O)NC(C6=NC7=C(C=C(C=C7)OC)C=C6O)=O)=O)C(C)(O)C)C)=O)C)=O)=O)([H])[C@H](CC=N2)OC(C)=O
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Synonyms
BBM-928 A
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Structure Classification
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Initial Source
Actinomadura luzonensis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Luzopeptin A Related Classifications
HY-130050 Related Classifications
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