AVN-322 free base
AVN-322 free base is an orally active, highly selective 5-HT6Rantagonist for central nervous system disease research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1194574-33-8
- Fòrmula: C17H19N5O2S
- Peso molecular:357.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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5-HT6 Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
6.16 μM
Compound: 5, AVN322
|
Antagonist activity at human recombinant 5HT2B receptor expressed in HEK293 cells assessed as inhibition of alphamethyl5HT-induced intracellular calcium mobilization by Fluo4-based staining method
Antagonist activity at human recombinant 5HT2B receptor expressed in HEK293 cells assessed as inhibition of alphamethyl5HT-induced intracellular calcium mobilization by Fluo4-based staining method
|
[PMID: 22664127] |
Chemical Information
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No. CAS 1194574-33-8
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Peso molecular 357.43
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Fòrmula C17H19N5O2S
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SMILES
O=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)