AZD1134
AZD1134 is an orally active, brain-penetrant and highly selective 5-HT1B receptor antagonist with IC50 values of 2.9 nM (human) and 0.108 nM (guinea pig), respectively. AZD1134 increases synaptic serotonin levels in guinea pigs. AZD1134 is promising for research of psychiatric disorders, such as depression and anxiety.
For research use only. We do not sell to patients.
- CAS No.: 442548-99-4
- Formula: C28H32FN5O4
- Molecular Weight:521.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Description
Chemical Information
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CAS No. 442548-99-4
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Molecular Weight 521.58
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Formula C28H32FN5O4
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SMILES
O=C(C1=CC(C2=C(O1)C(N3CCN(C)CC3)=CC(F)=C2)=O)NC4=CC=C(N5CCN(C(CC)=O)CC5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AZD1134 Related Classifications
HY-171794 Related Classifications
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