2. Protein Tyrosine Kinase/RTK
  3. Src
  4. BT424

BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model.

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BT424 Chemical Structure

BT424 Chemical Structure

CAS No. : 2755180-37-9

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Description

BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].

Molecular Weight

421.08

Formula

C22H15BCl2N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC2=C(OC(C(C3=NOB(C4=CC=CC=C4)N3)=C2)C5=CC=CC=C5)C(Cl)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
References
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BT424 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BT4242755180-37-9BT 424BT-424Srchematopoietic cell kinase (HCK)inflammationkidney fibrosisunilateral ureteral obstruction (UUO)macrophageInhibitorinhibitorinhibit

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