CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 2554877-43-7
- Formula: C21H32N8O2
- Molecular Weight:428.53
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Storage:
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CXCR4 1.25 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)[1]
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Dosage:10 mg/kg
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Administration:IP; single dosage
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Result:Significantly reduced the edema weights (∼50%) in the lesion and decreased the expression of CXCR4s.
Chemical Information
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CAS No. 2554877-43-7
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Appearance Solid
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Molecular Weight 428.53
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Formula C21H32N8O2
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SMILES
O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@@H](N)CCCNC(N)=N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CXCR4 modulator-2 Related Classifications
HY-146054 Related Classifications
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