LY86057
LY86057 is an ergoline derivative without N1 substituents. It has higher affinity for porcine, squirrel monkey and human 5-HT2 receptors than rats and is an antagonist of 5-HT2 receptors. When studying the differences in recognition of a series of ergolines between species, LY86057 was found to be more selective for 5-HT2 receptors. Compared with LY53857, LY108742 resulted in a higher affinity for rat 5-HT2 receptors even when the N1 substituent was only methyl.
For research use only. We do not sell to patients.
- CAS No.: 148966-66-9
- Formula: C20H26N2O3
- Molecular Weight:342.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 148966-66-9
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Molecular Weight 342.43
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Formula C20H26N2O3
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SMILES
CN1[C@@]2([H])[C@@](C[C@H](C1)C(OC(C)C(O)C)=O)([H])C3=CC=CC4=C3C(C2)=CN4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)