Phosphatase
Phosphatases are a group of hydrolases that catalyze the hydrolysis of a phosphomonoester, removing a phosphate moiety from the substrate. In contrast to kinases, which phosphorylate substrate, phosphatases dephosphorylate the substrate. Phosphorylation is a fundamental and pervasive mechanism widely known to regulate the functions of proteins. Phosphatases and kinases act as regulators of protein reversible phosphorylation in the cell, which constitutes a major form of signaling and an essential mechanism of regulation in all living organisms. Protein phosphatases are the enzymes that hydrolyze phospho-ester bonds in phosphorylated proteins. Eukaryotic protein phosphatases are structurally and functionally diverse enzymes that are represented by three distinct gene families, including the PPPs (phosphoprotein phosphatases), PPMs (metal-dependent protein phosphatases) and PTPs (protein tyrosine phosphatases). PPPs and PPMs dephosphorylate phosphoserine and phosphothreonine residues, whereas the PTPs dephosphorylate phosphotyrosine amino acids.
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Phosphatase Recombinant Proteins (66)
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Inhibitors & Agonists (685)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
