UBP 1112
UBP 1112 is a selective group III mGluR antagonist, with a Kd of 5.1 μM.UBP 1112 shows 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor.
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- CAS No.: 339526-74-8
- Formule: C10H14NO5P
- Masse moléculaire:259.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Kd: 5.1 μM (group III mGluR), 488 μM (group II mGluR)[1]
UBP 1112 antagonises the depression of the fast component of the dorsal root-evoked ventral root potential induced by (S)-AP4 with apparent KD of 5.1 μM. UBP 1112 also antagonises the (S)-AP4 induced depression of synaptic transmission, with pA2 of 5.3. In addition, UBP 1112 (1 mM) displays little or no activity on (S)-3,5-DHPG-, NMDA-, AMPA- or kainate-induced responses on motoneurones[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 339526-74-8
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Masse moléculaire 259.20
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Formule C10H14NO5P
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SMILES
OC(C(N)(C1=CC(C)=C(P(O)(O)=O)C=C1)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UBP 1112 Related Classifications
HY-107517 Related Classifications
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