CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 95.0%
- CAS No.: 2554877-43-7
- Formule: C21H32N8O2
- Masse moléculaire:428.53
-
Stockage:
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
CXCR4 1.25 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)[1]
-
Dosage:10 mg/kg
-
Administration:IP; single dosage
-
Result:Significantly reduced the edema weights (∼50%) in the lesion and decreased the expression of CXCR4s.
Chemical Information
-
CAS No. 2554877-43-7
-
Appearance Solid
-
Masse moléculaire 428.53
-
Formule C21H32N8O2
-
SMILES
O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@@H](N)CCCNC(N)=N
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
4°C, protect from light, stored under argon
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CXCR4 modulator-2 Related Classifications
HY-146054 Related Classifications
Powered by Bioz