D44
D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
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- CAS No.: 826998-10-1
- Formule: C16H16N4OS
- Masse moléculaire:312.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Chemical Information
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CAS No. 826998-10-1
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Masse moléculaire 312.39
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Formule C16H16N4OS
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SMILES
O=C(CSC1=NC2=CC=CN=C2N1)NC3=CC=CC=C3CC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Atack TC, et al. Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35. ACS Med Chem Lett. 2020 Sep 1;11(11):2131-2138. [Content Brief]
[2]. Harikishore A, et al. Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent[J]. Scientific reports, 2013, 3(1): 2501. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D44 Related Classifications
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