Danitracen
Danitracen (NSC 170955) is an orally active, CNS penetrant serotonin antagonist with antidepressant activity. Danitracen reduces serotonin levels in the cerebrum, cerebellum, medulla and the whole brain. Danitracen exhibits anticataleptic effects in rat catalepsy models. Danitracen can be used for catalepsy and depression research.
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- CAS No.: 31232-26-5
- Formule: C20H21NO
- Masse moléculaire:291.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 31232-26-5
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Masse moléculaire 291.39
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Formule C20H21NO
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SMILES
OC1C2=C(C=CC=C2)/C(C3=CC=CC=C13)=C4CCN(C)CC/4
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Synonyms
NSC 170955; WA 335
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Maj J, et al. Influence of WA-335, a factor which blocks serotonin receptors, on neuroleptic-induced catalepsy. Arch Immunol Ther Exp (Warsz). 1976;24(2):197-203. [Content Brief]
[2]. Kaumeier S, et al. WA 335 (danitracen): a preliminary evaluation of a potential antidepressant compound. A comparative double-blind study with WA 335 and amitriptyline in the treatment of depressive patients. Curr Ther Res Clin Exp. 1977 Jan;21(1):108-13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)