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Cat. No.: HY-N20701

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Eucomic acid

Name: Eucomic acid
Brand: MedChemExpress
SKU: HY-N20701
Price: 420.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Eucomic acid is a derivative of Malic acid (HY-Y1311). Eucomic acid also acts as an anti-plasmodial inhibitor, pigment inducer and antioxidant. Eucomic acid inhibits the growth of Plasmodium falciparum. Eucomic acid promotes the production of black pigments in mature soybean pods and seed coats through oxidation or polymerization, while exerting antioxidant effects. Eucomic acid can be isolated from the roots of Eriosema montanum and the bulbs of Eucomis punctata. Eucomic acid can be used in research on malaria, antioxidation, etc.

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CAS No.: 60449-48-1
Formule: C₁₁H₁₂O₆
Masse moléculaire:240.21

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eucomic acid Chemical Structure

CAS No.: 60449-48-1

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Activité biologique
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- In Vitro
Chemical Information
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Activité biologique

Description

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In Vitro

Eucomic acid (structure 1) potently inhibits the growth of Plasmodium falciparum strain 3D7 in vitro after 48 h, with an IC₅₀ value of 0.057 µg/mL^[1].
Eucomic acid (3 days) exhibits extremely low cytotoxicity against the human acute leukemia cell line THP-1 in vitro, with a CC₅₀ value of 374.9 µg/mL^[1].
Eucomic acid (4.1 μg/g FW; 3 days) is abundant in the black pods of soybean lines expressing functional L1 (R171-BLk, L1-OE1), and together with Piscidic acid (HY-N11707), it promotes the formation of black pigments in mature soybean pods^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 60449-48-1
Masse moléculaire 240.21
Formule C₁₁H₁₂O₆
SMILES

OC(C[C@](C(O)=O)(O)CC1=CC=C(C=C1)O)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Tomani, J.C.D., et al. In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of Eriosema montanum Baker f. (Fabaceae). Molecules 2021, 26, 2795.

[2]. Lyu X, et al. The domestication-associated L1 gene encodes a eucomic acid synthase pleiotropically modulating pod pigmentation and shattering in soybean. Molecular plant. 2023 Jul 03;16(7):1178-1191. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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