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Cat. No.: HY-105324

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GRC-6211

GRC-6211 is an orally active and selective TRPV1 antagonist. GRC-6211 exhibits anti-inflammation effect.

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CAS No.: 1166398-35-1
Formule: C₂₂H₂₁N₃O₂
Masse moléculaire:359.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

GRC-6211 Chemical Structure

CAS No.: 1166398-35-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

GRC-6211 is an orally active and selective TRPV1 antagonist. GRC-6211 exhibits anti-inflammation effect^[1].

IC₅₀ & Target^[1]

TRPV1

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In Vivo

GRC-6211 (0.001-1 mg/kg, through a duodenal catheter) decreases bladder overactivity and noxious bladder input in cystitis rats models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1166398-35-1
Masse moléculaire 359.42
Formule C₂₂H₂₁N₃O₂
SMILES

O=C(NC1=CC=CC2=C1C=CN=C2)N[C@@H]3CC4(CCC4)OC5=CC=CC=C53
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Charrua A, et al. GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models. J Urol. 2009 Jan;181(1):379-86. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- In Vivo
Chemical Information
Pureté et documentation
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GRC-6211

Voir tous les produits spécifiques à Isoform TRP Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GRC-6211 Related Classifications

HY-105324 Related Classifications