HBF-0079
HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma.
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- CAS No.: 315702-93-3
- Formule: C12H9N5S
- Masse moléculaire:255.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 10
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Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
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[PMID: 18774291] |
| Huh-7 | CC50 |
1.1 μM
Compound: HBF-0079
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Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
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[PMID: 27793566] |
Chemical Information
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CAS No. 315702-93-3
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Masse moléculaire 255.30
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Formule C12H9N5S
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SMILES
C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HBF-0079 Related Classifications
HY-18203 Related Classifications
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