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Cat. No.: HY-183994

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HL82624

HL82624 is a CXCR4 agnoist. HL82624 triggers CXCR4-mediated cell migration. HL82624 can be used for the research of neurodegenerative diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₃₃H₅₁N₁₁O₄
Masse moléculaire:665.83

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HL82624 Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

HL82624 is a CXCR4 agnoist. HL82624 triggers CXCR4-mediated cell migration. HL82624 can be used for the research of neurodegenerative diseases^[1].

IC₅₀ & Target^[1]

CXCR4

Voir tous les produits spécifiques à Isoform CXCR :

In Vitro

HL82624 reduces CXCR4 activation energy barriers for all transition states, and facilitates early-stage CXCR4 activation^[1].
HL82624 binds to CXCR4 on Sup-T1 cells with an IC₅₀ of 24 μM^[1].
HL82624 (1-100 μM; 3 h) promotes CXCR4-mediated cell migration in Sup-T1 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Migration Assay ^[1]

Cell Line:

Sup-T1 cells
Concentration:

1; 10; 50; 100 μM
Incubation Time:

3 h
Result:

Showed maximal activity observed at 10-50 μM.
Promoted CXCR4-mediated cell migration.

Chemical Information

Masse moléculaire 665.83
Formule C₃₃H₅₁N₁₁O₄
SMILES

NC(NCCC[C@H](NCC1=CC=CC=N1)C(NCC2=CC(C[C@H](NC([C@H]3N(C([C@@H](N)CCCCN)=O)CCC3)=O)C(N)=O)=CC=C2)=O)=N
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Zhou J, et al. Computational Insights into the Activation Mechanism of CXCR4: Implications for the Design of Small Molecule Agonists. J Am Chem Soc. 2026;148(20):20545-20554. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Cat. No.:
Quantité:
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HL82624

Voir tous les produits spécifiques à Isoform CXCR