hsa62
hsa62 is a dual inhibitor for SIRT1 and SIRT2, with IC50 of 1.3 and 5.5 μM, respectively.
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- CAS No.: 780822-35-7
- Formule: C19H14N6O4S2
- Masse moléculaire:454.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
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SIRT1 1.3 μM (IC50) |
SIRT2 5.5 μM (IC50) |
SIRT3 43.6 μM (IC50) |
Chemical Information
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CAS No. 780822-35-7
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Masse moléculaire 454.48
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Formule C19H14N6O4S2
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SMILES
O=C1NC2=CC=C(S(=O)(NC3=CC(SC4=NN=CN4)=C(C5=C3C=CC=C5)O)=O)C=C2N1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)