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Cat. No.: HY-118410

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L-738167

L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research.

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CAS No.: 163212-43-9
Formule: C₂₅H₃₄N₆O₆S
Masse moléculaire:546.64

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

L-738167 Chemical Structure

CAS No.: 163212-43-9

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Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG) Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)	[PMID: 9191954]
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin	[PMID: 9191954]
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN) Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)	[PMID: 9191954]

Chemical Information

CAS No. 163212-43-9
Masse moléculaire 546.64
Formule C₂₅H₃₄N₆O₆S
SMILES

O=C(O)[C@H](CNC(C1=NN2C(C(N(CCC3CCNCC3)CCC2)=O)=C1)=O)NS(=O)(C4=CC=C(C)C=C4)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Terence G, et al. Non-peptide fibrinogen receptor antagonists. 21. The synthesis of [3H]L-738,167. Journal of Labelled Compounds and Radiopharmaceuticals. Volume41, Issue4. April 1998

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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L-738167

Voir tous les produits spécifiques à Isoform Integrin

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

L-738167 Related Classifications

HY-118410 Related Classifications