Lubiprostone-d7
Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
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- CAS No.: 1217675-13-2
- Formule: C20H25D7F2O5
- Masse moléculaire:397.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217675-13-2
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Unlabeled Cas 136790-76-6
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Masse moléculaire 397.51
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Formule C20H25D7F2O5
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SMILES
C(CC(C(CC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])(F)F)=O)[C@@H]1[C@@H](CCCCCCC(O)=O)C(=O)C[C@H]1O
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Synonyms
RU-0211-d7; SPI-0211-d7
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lubiprostone-d7 Related Classifications
HY-B0679S Related Classifications
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