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Tabalumab

(Synonyms: LY2127399)
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Tabalumab (LY2127399) is a human anti-BAFF (B-cell activating factor) monoclonal antibody (IgG4 type) with neutralising activity against membrane bound and soluble BAFF. Tabalumab can be used in studies of autoimmune diseases such as rheumatoid arthritis, renal failure and systemic lupus erythematosus.

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  • Pureté : 99%
  • CAS No.: 1143503-67-6
  • Masse moléculaire:145.97 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tabalumab
  • Experimental Validation Results for Tabalumab
  • Experimental Validation Results for Tabalumab
  • Tabalumab Chemical Structure
    Tabalumab Chemical Structure
CAS No.: 1143503-67-6
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Tabalumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Loaded BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag, HY-P78384) on ProA biosensor, can bind Tabalumab with an affinity constant of 4.080E-10 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1.5×106 THP-1 cells labeling Tabalumab (HY-P99220, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 (S228P) kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tabalumab Chemical Structure
    1/16
  • Tabalumab
  • Loaded BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag, HY-P78384) on ProA biosensor, can bind Tabalumab with an affinity constant of 4.080E-10 M as determined in BLI assay.
  • Flow cytometric analysis of 1.5×106 THP-1 cells labeling Tabalumab (HY-P99220, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 (S228P) kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).