VU0463841
VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research.
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- CAS No.: 1439095-16-5
- Formule: C13H8ClFN4O
- Masse moléculaire:290.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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mGlu5 Receptor 13 nM (IC50) |
Chemical Information
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CAS No. 1439095-16-5
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Masse moléculaire 290.68
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Formule C13H8ClFN4O
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SMILES
O=C(NC1=NC=C(C=C1)Cl)NC2=CC(F)=CC(C#N)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)