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Art. -Nr.: HY-N19700

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Calphostin D

Calphostin D is a protein kinase C (Protein Kinase, PKC) inhibitor with an IC₅₀ of 6.4 μM. Calphostin D achieves selective inhibition by interacting with the unique C1 regulatory domain of PKC. As a photosensitizer, Calphostin D generates reactive oxygen species upon exposure to light. Calphostin D can be used in cancer-related research.

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CAS. Nr.: 124986-26-1
Formel: C₃₀H₃₀O₁₀
Molecular Weight:550.55

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Calphostin D Chemical Structure

CAS. Nr.: 124986-26-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

PKC

6.4 μM (IC₅₀)

Alle PKC Isoform-spezifische Produkte anzeigen :

In Vitro

Calphostin D inhibits full-length PKC with an IC₅₀ of 6.4 μM, acting via the enzyme's regulatory domain^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 124986-26-1
Molecular Weight 550.55
Formel C₃₀H₃₀O₁₀
SMILES

O=C(C1=C2C(C3=C(OC)C=C(O)C4=C53)=C(OC)C=C1O)C(OC)=C(C[C@H](O)C)C2=C5C(C[C@H](O)C)=C(OC)C4=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Morgan BJ, et al. Design, synthesis, and investigation of protein kinase C inhibitors: total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones. Journal of the American Chemical Society. 2009 Jul 08;131(26):9413-25. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Calphostin D

Alle PKC Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Calphostin D Related Classifications

HY-N19700 Related Classifications