2650188-32-0
Chemical Structure
Purinostat mesylate
- CAS No.: 2650188-32-0
- Formula:C24H30N10O6S
- Molecular Weight:586.62
IUPAC Name: 2-(((2-(4-aminophenyl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)(methyl)amino)-N-hydroxypyrimidine-5-carboxamide methanesulfonate
InChIKey: QTSZBNQPNSJXAC-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N(CC2=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C3N2C)C)N=C1)NO.O=S(O)(C)=O
Biological Activity: Purinostat mesylate is a selective inhibitor of HDAC. Purinostat mesylate inhibits class I and class IIb HDACs with IC50s from 0.81 to 11.5 nM. Purinostat mesylate induces apoptosis and affects cell cycle of LAMA84 and 188 BL-2 cells, and shows potently anti-leukemia effects in vivo. Purinostat mesylate can be used for the research of lymphoblastic leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Purinostat mesylate | 99.45% | Purinostat mesylate is a selective inhibitor of HDAC. Purinostat mesylate inhibits class I and class IIb HDACs with IC50s from 0.81 to 11.5 nM. Purinostat mesylate induces apoptosis and affects cell cycle of LAMA84 and 188 BL-2 cells, and shows potently anti-leukemia effects in vivo. Purinostat mesylate can be used for the research of lymphoblastic leukemia. | ||||||||||||||||||||
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Keywords
