2. Apoptosis
  3. Caspase Apoptosis
  4. Caspase-3 activator 3

Caspase-3 activator 3 (compound 2h) induces apoptosis in HL-60 and K562 cells via significant caspase 3 activation. Caspase-3 activator 3 shows antileukemic acticity against HL-60 and K562 cells, with IC50 values of 42.89 and 33.61 μM, respectively.

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Caspase-3 activator 3 Chemical Structure

Caspase-3 activator 3 Chemical Structure

CAS No. : 2999724-52-4

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Caspase-3 activator 3 Related Antibodies

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Description

Caspase-3 activator 3 (compound 2h) induces apoptosis in HL-60 and K562 cells via significant caspase 3 activation. Caspase-3 activator 3 shows antileukemic acticity against HL-60 and K562 cells, with IC50 values of 42.89 and 33.61 μM, respectively[1].

IC50 & Target

Caspase 3

 

Molecular Weight

481.45

Formula

C24H25BrN4S
CAS No.
SMILES

CN1CCN(C2=CC=C(C3CC(C4=CSC=C4)=NN3C5=CC=CC(Br)=C5)C=C2)CC1
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Caspase-3 activator 3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caspase-3 activator 32999724-52-4CaspaseApoptosisHL-60K562 cellantileukemicInhibitorinhibitorinhibit

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