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Art. -Nr.: HY-14231

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CCR5 antagonist 5

1 Cited Publications

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CCR5 antagonist 5 (compound example 11) is a CCR5 antagonist. CCR5 antagonist 5 has the potential to study inflammation and immunity and viral (such as HIV) infection.

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CAS. Nr.: 869725-27-9
Formel: C₃₀H₄₂Cl₂F₃N₅O₂
Molecular Weight:632.59

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CCR5 antagonist 5 Chemical Structure

CAS. Nr.: 869725-27-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Beschreibung

CCR5 antagonist 5 (compound example 11) is a CCR5 antagonist. CCR5 antagonist 5 has the potential to study inflammation and immunity and viral (such as HIV) infection^[1].

IC₅₀ & Target

CCR5^[1].

Alle CCR Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 869725-27-9
Molecular Weight 632.59
Formel C₃₀H₄₂Cl₂F₃N₅O₂
SMILES

FC(F)(F)C1=CC2=C([C@@H](N3CCN(C4(C)CCN(C(C5=C(C)N=CN=C5C)=O)CC4)C[C@@H]3C)[C@H](OCC)C2)C=C1.Cl.Cl
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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APL Bioeng

Quercetin targets the Ccl4-Ccr5 axis to relieve neuropathic pain after spinal cord injury. [Abstract]

2025 Jul 24;9(3):036108. PMID: 40717840

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Discovery of INCB9471, a Potent, Selective, and Orally Bioavailable CCR5 Antagonist with Potent Anti-HIV-1 Activity ACC MCL Publication Date (Web): August 25, 2010 (Letter)

[2]. Chu-Biao Xue, et al. Piperazinylpiperidine derivatives as chemokine receptor antagonists. US20050261310A1.

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

CCR5 antagonist 5

1 Cited Publications

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CCR5 antagonist 5

Publications Citing Use of MedChemExpress (MCE) CCR5 antagonist 5

Alle CCR Isoform-spezifische Produkte anzeigen

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CCR5 antagonist 5 Related Classifications

HY-14231 Related Classifications