D44
D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
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- CAS. Nr.: 826998-10-1
- Formel: C16H16N4OS
- Molecular Weight:312.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 826998-10-1
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Molecular Weight 312.39
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Formel C16H16N4OS
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SMILES
O=C(CSC1=NC2=CC=CN=C2N1)NC3=CC=CC=C3CC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Atack TC, et al. Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35. ACS Med Chem Lett. 2020 Sep 1;11(11):2131-2138. [Content Brief]
[2]. Harikishore A, et al. Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent[J]. Scientific reports, 2013, 3(1): 2501. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
D44 Related Classifications
HY-W046346 Related Classifications
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