Danitracen
Danitracen (NSC 170955) is an orally active, CNS penetrant serotonin antagonist with antidepressant activity. Danitracen reduces serotonin levels in the cerebrum, cerebellum, medulla and the whole brain. Danitracen exhibits anticataleptic effects in rat catalepsy models. Danitracen can be used for catalepsy and depression research.
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- CAS. Nr.: 31232-26-5
- Formel: C20H21NO
- Molecular Weight:291.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 31232-26-5
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Molecular Weight 291.39
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Formel C20H21NO
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SMILES
OC1C2=C(C=CC=C2)/C(C3=CC=CC=C13)=C4CCN(C)CC/4
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Synonyms
NSC 170955; WA 335
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Maj J, et al. Influence of WA-335, a factor which blocks serotonin receptors, on neuroleptic-induced catalepsy. Arch Immunol Ther Exp (Warsz). 1976;24(2):197-203. [Content Brief]
[2]. Kaumeier S, et al. WA 335 (danitracen): a preliminary evaluation of a potential antidepressant compound. A comparative double-blind study with WA 335 and amitriptyline in the treatment of depressive patients. Curr Ther Res Clin Exp. 1977 Jan;21(1):108-13. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)