Trpv3 - transient receptor potential cation channel, subfamily V, member 3 Gene

Also Known as Nh; VRL3; 1110036I10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 246788

Summary

Enables cation channel activity. Acts upstream of or within response to temperature stimulus. Located in membrane. Is expressed in central nervous system and sensory organ. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in colorectal cancer; congenital stationary night blindness; keratosis (multiple); migraine with aura; and schizophrenia. Orthologous to human TRPV3 (transient receptor potential cation channel subfamily V member 3). [provided by Alliance of Genome Resources, Apr 2022]

Trpv3 Products (2)

mRNA Protein Name
NM_001371006.1 NP_001357935.1 transient receptor potential cation channel subfamily V member 3 isoform 2
NM_145099.3 NP_659567.2 transient receptor potential cation channel subfamily V member 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
12016205 MGI
enables monoatomic ion channel activity IDA
IDA: Inferred from direct assay
15194687 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20403327 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within response to temperature stimulus IDA
IDA: Inferred from direct assay
12016205 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in membrane IDA
IDA: Inferred from direct assay
12016205 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily V member 3

  • TRP ion channel TRPV3

  • non-hair

Trpv3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Cross
Trpv3 Q8K424 EGFR Homo sapiens P00533
Anti Tag CoIP
20403327
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Art. -Nr. Produktname Wirkung
Reinheit Rare Diseases
HY-N0808 Camphor Agonist 98.0% Unkown
HY-B1239 Drofenine hydrochloride 98.10% Unkown
HY-B1239A Drofenine / Unkown

Pre-clinical Phase

Bioactive Molecules (6)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-165559 Trpvicin Inhibitor 99.4% Unkown
HY-131868 TRPV3 antagonist 74a Antagonist 99.85% Unkown
HY-125527A 17(R)-Resolvin D1 Inhibitor 99.69% Unkown
HY-186172 KS0365 Activator / Unkown
HY-183281 TRPV3 antagonist-1 Antagonist / Unkown
HY-118535 N-Oleoyl valine Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpv3 NCBI NCBI:162514