CEP44 - centrosomal protein 44 Gene

Also Known as PS1TP3; KIAA1712

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80817

About CEP44

This gene has 10 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in testis (RPKM 3.4), endometrium (RPKM 3.1) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in centriole replication and centriole-centriole cohesion. Located in centriole; centrosome; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]

CEP44 Products (2)

mRNA Protein Name
NM_001040157.3 NP_001035247.1 centrosomal protein of 44 kDa isoform a
NM_001145314.2 NP_001138786.1 centrosomal protein of 44 kDa isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables microtubule binding IDA
IDA: Inferred from direct assay
32060285 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in centriole replication IDA
IDA: Inferred from direct assay
32060285 GOA
involved in centriole-centriole cohesion IMP
IMP: Inferred from mutant phenotype
31974111 GOA
involved in centrosome cycle IMP
IMP: Inferred from mutant phenotype
31974111 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in centriole IDA
IDA: Inferred from direct assay
32060285 GOA
located in centrosome IDA
IDA: Inferred from direct assay
21399614 GOA
located in spindle pole IDA
IDA: Inferred from direct assay
21399614 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEP44 Protein Structure

CEP44

CEP44: Centrosomal spindle body, CEP44 (5 - 135)

  • 0
  • 100
  • 200
  • 300
  • 390 a.a.
Protein Preferred Names Protein Names

centrosomal protein of 44 kDa

  • HBV PreS1-transactivated protein 3

CEP44 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CEP44 Q9C0F1 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Array
25416956
Intra
CEP44 Q9C0F1 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 CEP57L1 Homo sapiens Q8IYX8-2
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 LRRFIP1 Homo sapiens Q32MZ4-4
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 LRRFIP1 Homo sapiens Q32MZ4-4
Y2H Array
25416956
Intra
CEP44 Q9C0F1 GNG11 Homo sapiens Q53Y01
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 GNG11 Homo sapiens Q53Y01
Y2H Array
25416956
Intra
CEP44 Q9C0F1 GNG11 Homo sapiens Q53Y01
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 FAM74A4 Homo sapiens Q5TZK3
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 FAM74A4 Homo sapiens Q5TZK3
Y2H Array
25416956
Intra
CEP44 Q9C0F1 CCDC146 Homo sapiens Q8IYE0-2
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 CCDC146 Homo sapiens Q8IYE0-2
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 MGC24125 Homo sapiens Q8NEQ2
Y2H Array
25416956
Intra
CEP44 Q9C0F1 MGC24125 Homo sapiens Q8NEQ2
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 DHX57 Homo sapiens Q6P158
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 DHX57 Homo sapiens Q6P158
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 DHX57 Homo sapiens Q6P158
Y2H Array
25416956
Intra
CEP44 Q9C0F1 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Intra
CEP44 Q9C0F1 HAUS1 Homo sapiens Q96CS2
BioID
26638075
Intra
CEP44 Q9C0F1 HAUS1 Homo sapiens Q96CS2
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 DIP2A Homo sapiens Q14689
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 DIP2A Homo sapiens Q14689
Y2H Array
25416956
Intra
CEP44 Q9C0F1 CAB39 Homo sapiens Q9Y376
Validated Y2H
32296183
Intra
CEP44 Q9C0F1 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 BYSL Homo sapiens Q13895
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 TXLNA Homo sapiens P40222
Y2H Array
25416956
Intra
CEP44 Q9C0F1 CDC23 Homo sapiens Q9UJX2
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 CDC23 Homo sapiens Q9UJX2
Y2H Array
25416956
Intra
CEP44 Q9C0F1 BLOC1S6 Homo sapiens Q9UL45
Validated Y2H
32296183
Intra
CEP44 Q9C0F1 ING5 Homo sapiens Q8WYH8
Y2H Array
25416956
Intra
CEP44 Q9C0F1 ING5 Homo sapiens Q8WYH8
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 MLLT6 Homo sapiens Q6P2C6
Y2H Array
25416956
Intra
CEP44 Q9C0F1 MLLT6 Homo sapiens Q6P2C6
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 ERAL1 Homo sapiens O75616
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 ERAL1 Homo sapiens O75616
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 ERAL1 Homo sapiens O75616
Y2H Array
25416956
Intra
CEP44 Q9C0F1 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 ZNF587 Homo sapiens Q96SQ5
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 H2AP Homo sapiens O75409
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 H2AP Homo sapiens O75409
Y2H Array
25416956
Intra
CEP44 Q9C0F1 TCEA2 Homo sapiens Q15560
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 TCEA2 Homo sapiens Q15560
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 MAPK9 Homo sapiens P45984
Y2H Array
25416956
Intra
CEP44 Q9C0F1 DCTN2 Homo sapiens Q13561
BioID
26638075
Intra
CEP44 Q9C0F1 TRIM41 Homo sapiens Q8WV44
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 FXR2 Homo sapiens P51116
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 FXR2 Homo sapiens P51116
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 FXR2 Homo sapiens P51116
Y2H Array
25416956
Intra
CEP44 Q9C0F1 ZNF417 Homo sapiens Q8TAU3
Y2H
21516116
Intra
CEP44 Q9C0F1 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 CHIC2 Homo sapiens Q9UKJ5
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 CHIC2 Homo sapiens Q9UKJ5
Y2H Array
25416956
Intra
CEP44 Q9C0F1 CBY2 Homo sapiens Q8NA61
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 CBY2 Homo sapiens Q8NA61
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 CBY2 Homo sapiens Q8NA61
Y2H Pooling
16189514
Intra
CEP44 Q9C0F1 ABI3 Homo sapiens Q9P2A4
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 ABI3 Homo sapiens Q9P2A4
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Intra
CEP44 Q9C0F1 ABI3 Homo sapiens Q9P2A4
Y2H Array
25416956
Intra
CEP44 Q9C0F1 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
25416956
Intra
CEP44 Q9C0F1 AQP1 Homo sapiens P29972
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 AQP1 Homo sapiens P29972
Y2H Array
25416956
Intra
CEP44 Q9C0F1 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 SCNM1 Homo sapiens Q9BWG6
Y2H Array
25416956
Intra
CEP44 Q9C0F1 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 MRFAP1L1 Homo sapiens Q96HT8
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 MRFAP1L1 Homo sapiens Q96HT8
Y2H Array
25416956
Intra
CEP44 Q9C0F1 LMO1 Homo sapiens P25800
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 LMO1 Homo sapiens P25800
Validated Y2H
25416956
Intra
CEP44 Q9C0F1 LMO1 Homo sapiens P25800
Y2H Array
25416956
Intra
CEP44 Q9C0F1 ZFYVE26 Homo sapiens Q68DK2-5
Y2H Prey Pooling
25416956
Intra
CEP44 Q9C0F1 ZFYVE26 Homo sapiens Q68DK2-5
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Retinitis Pigmentosa 29

  • RP29
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-181772 MCULE-3064932370 Inhibitor / Unkown
HY-RS02516 CEP44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CEP44 VGNC VGNC:39129
Bos taurus CEP44 VGNC VGNC:27205
Macaca mulatta CEP44 VGNC VGNC:71134
Rattus norvegicus CEP44 RGD RGD:1308517
Mus musculus CEP44 MGD MGI:3525111
Felis catus CEP44 VGNC VGNC:60775
Others CEP44 NCBI