HBF-0079
HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma.
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- CAS. Nr.: 315702-93-3
- Formel: C12H9N5S
- Molecular Weight:255.30
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 10
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Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
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[PMID: 18774291] |
| Huh-7 | CC50 |
1.1 μM
Compound: HBF-0079
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Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
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[PMID: 27793566] |
Chemical Information
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CAS. Nr. 315702-93-3
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Molecular Weight 255.30
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Formel C12H9N5S
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SMILES
C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HBF-0079 Related Classifications
HY-18203 Related Classifications
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