Picrasidine J
Picrasidine J is a selective inhibitor targeting the KLK-10 protease and the ERK signaling pathway. Picrasidine J inhibits epithelial-mesenchymal transition (EMT) by upregulating E-Cadherin and ZO-1 and downregulating β-catenin and Snail, while simultaneously reducing KLK-10 expression and inhibiting ERK phosphorylation, thereby exhibiting significant anti-migratory and anti-invasive activity. Picrasidine J can inhibit the metastasis of head and neck squamous cell carcinoma (HNSCC) and is primarily used in anti-metastasis research for head and neck tumors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 100234-62-6
- Formel: C14H14N2O2
- Molecular Weight:242.27
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
KLK10 |
E-cadherin (CDH1) |
Chemical Information
-
CAS. Nr. 100234-62-6
-
Molecular Weight 242.27
-
Formel C14H14N2O2
-
SMILES
OC1=CC=CC2=C1NC3=C2C(OC)=CN=C3CC
-
Structure Classification
-
Initial Source
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Picrasidine J Related Classifications
HY-N16719 Related Classifications
Powered by Bioz