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Art. -Nr.: HY-N8331

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Terpendole I

Terpendole I is a fungal indole diterpenoid and an ACAT inhibitor (IC₅₀ = 145 µM). Terpendole I can be used in studies related to lipid metabolism.

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CAS. Nr.: 167612-17-1
Formel: C₂₇H₃₅NO₅
Molecular Weight:453.57

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Terpendole I Chemical Structure

CAS. Nr.: 167612-17-1

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Terpendole I is a fungal indole diterpenoid and an ACAT inhibitor (IC₅₀ = 145 µM). Terpendole I can be used in studies related to lipid metabolism^[1]^[2].

IC₅₀ & Target^[1]

Microbial Metabolite

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Alle Acyltransferase Isoform-spezifische Produkte anzeigen :

In Vitro

Terpendole I weakly inhibits ACAT activity in rat liver microsomes with an IC₅₀ of 145 μM^[1].
Terpendole I (1 mg/mL (10 μg/paper disk); 24 h (bacteria); 48 h (fungi, yeasts)) shows no antimicrobial activity against tested bacteria, fungi, and yeasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 167612-17-1
Molecular Weight 453.57
Formel C₂₇H₃₅NO₅
SMILES

C[C@@]12[C@@]([H])(CC[C@]3([C@]45[C@]([H])(CC[C@@]32C)O[C@@H]([C@H]([C@H]4O5)O)C(O)(C)C)O)CC6=C1NC7=C6C=CC=C7
Structure Classification
- Alkaloids
- Indole Alkaloids
- Terpenoids
- Diterpenoids
Initial Source
- Microorganisms
Albophoma yamanashiensis
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Tomoda H, et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components. J Antibiot (Tokyo). 1995;48(8):793-804. [Content Brief]

[2]. Xu LL, et al. Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp. J Nat Prod. 2019;82(2):221-231. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Terpendole I

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Alle Acyltransferase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Terpendole I Related Classifications

HY-N8331 Related Classifications