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Art. -Nr.: HY-176416

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USP7-IN-17

USP7-IN-17 (compound M15) is a potent USP7 inhibitor. USP7-IN-17 inhibits HepG2 cell activity with an IC₅₀ of 4.38 μM.

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CAS. Nr.: 1174836-23-7
Formel: C₂₂H₂₃N₅OS
Molecular Weight:405.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

USP7-IN-17 Chemical Structure

CAS. Nr.: 1174836-23-7

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Preis

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Menge

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

USP7-IN-17 (compound M15) is a potent USP7 inhibitor. USP7-IN-17 inhibits HepG2 cell activity with an IC₅₀ of 4.38 μM^[1].

Alle Deubiquitinase Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 1174836-23-7
Molecular Weight 405.52
Formel C₂₂H₂₃N₅OS
SMILES

O=C(CNCCCN1C=CN=C1)NC2=CC=C(C=C2)C(S3)=NC4=C3C=C(C)C=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Srivastava M, et al. Rational Computational Workflow for Structure-Guided Discovery of a Novel USP7 Inhibitor. J Chem Inf Model. 2025 May 12;65(9):4468-4487. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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