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Cat. No.: HY-U00356

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Tertatolol

(Synonyms: (±)-Tertatolol; Racemic Tertatolol; dl-Tertatolol)

Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

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CAS No.: 83688-84-0
Formule: C₁₆H₂₅NO₂S
Masse moléculaire:295.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Tertatolol Chemical Structure

CAS No.: 83688-84-0

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- In Vitro
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Activité biologique

Description

Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

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Voir tous les produits spécifiques à Isoform 5-HT Receptor :

In Vitro

In serum-free media, tertatolol does not significantly alter the incorporation of ³H-thymidine after 28 h of incubation in human mesangial cell (HMC). In the presence of 1% serum, tertatolol significantly reduces ³H-thymidine incorporation. Tertatolol also inhibits ³H incorporation when PDGF and thrombin are used as the stimulus. Tertatolol inhibits the reduction in planar surface area of HMC induced by angiotensin II. The inhibitory effect of tertatolol on HMC proliferation is also potentiated by ritanserin and MDL 72222, 5HT2 and 5HT3 antagonists, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 83688-84-0
Masse moléculaire 295.44
Formule C₁₆H₂₅NO₂S
SMILES

OC(CNC(C)(C)C)COC1=C2C(CCCS2)=CC=C1
Synonyms

(±)-Tertatolol; Racemic Tertatolol; dl-Tertatolol
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shultz P, et al. Tertatolol: a beta-blocker with unique effects on human glomerular cell function. Cardiology. 1993;83 Suppl 1:51-6. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Tertatolol

Voir tous les produits spécifiques à Isoform Adrenergic Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

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Tertatolol Related Classifications

HY-U00356 Related Classifications