Anpirtoline
Anpirtoline (D-16949) is a centrally acting 5-HT1B receptor agonist, with Kis of 28 nM (5-HT1B), 150 nM (5-HT1A) and 1.49 μM (5-HT2). Anpirtoline has serotonergic, antinociceptive, antidepressant-like effects.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 98330-05-3
- Formule: C10H13ClN2S
- Masse moléculaire:228.74
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform 5-HT Receptor
More
Activité biologique
|
5-HT1A Receptor |
5-HT1B Receptor |
Chemical Information
-
CAS No. 98330-05-3
-
Masse moléculaire 228.74
-
Formule C10H13ClN2S
-
SMILES
ClC1=NC(SC2CCNCC2)=CC=C1
-
Synonyms
D-16949
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Swedberg MD, et al. D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat. J Pharmacol Exp Ther. 1992 Dec;263(3):1015-22. [Content Brief]
[2]. Chien PY, et al. The dorsal raphe-to-ventral hippocampal projection modulates reactive aggression through 5-HT1B receptors. Eur J Pharmacol. 2024 Oct 15;981:176918. [Content Brief]
[3]. Schlicker E, et al. Anpirtoline, a novel, highly potent 5-HT1B receptor agonist with antinociceptive/antidepressant-like actions in rodents. Br J Pharmacol. 1992 Mar;105(3):732-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anpirtoline Related Classifications
HY-101100A Related Classifications
Powered by Bioz