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Cat. No.: HY-113273

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Ap5A

(Synonyms: Diadenosine pentaphosphate)

Ap5A (Diadenosine pentaphosphate), a diadenosine polyphosphate, is an adenylate kinase inhibitor with a K_i of 2.5 nM. Ap5A can be used for study of cancer.

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CAS No.: 41708-91-2
Formule: C₂₀H₂₉N₁₀O₂₂P₅
Masse moléculaire:916.37

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Ap5A Chemical Structure

CAS No.: 41708-91-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Ap5A (Diadenosine pentaphosphate), a diadenosine polyphosphate, is an adenylate kinase inhibitor with a K_i of 2.5 nM. Ap5A can be used for study of cancer^[1].

IC₅₀ & Target

Human Endogenous Metabolite

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Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>=5 μM Compound: Ap5A	Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase	[PMID: 16539385]
PC-12	IC₅₀	29 μM Compound: 4	Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis	[PMID: 23751098]

Chemical Information

CAS No. 41708-91-2
Masse moléculaire 916.37
Formule C₂₀H₂₉N₁₀O₂₂P₅
SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C=NC4=C(N)N=CN=C43)(O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N5C6=NC=NC(N)=C6N=C5
Synonyms

Diadenosine pentaphosphate
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Bone R, et al. Inhibition of thymidine kinase by P1-(adenosine-5')-P5-(thymidine-5')-pentaphosphate. J Biol Chem. 1986 May 5;261(13):5731-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Ap5A

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Ap5A Related Classifications

HY-113273 Related Classifications