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Cat. No.: HY-103092

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CP-135807

CP-135807 is an orally active and selective 5-HT1D agonist (IC₅₀=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research.

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CAS No.: 151272-90-1
Formule: C₁₉H₂₁N₅O₂
Masse moléculaire:351.40

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

CP-135807 Chemical Structure

CAS No.: 151272-90-1

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Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

CP-135807 is an orally active and selective 5-HT1D agonist (IC₅₀=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research^[1]^[2].

IC₅₀ & Target^[1]^[2]

5-HT_1D Receptor

3.1 nM (IC₅₀, rat)

5-HT_1D Receptor

33 nM (IC₅₀, bovine)

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

In Vivo

Pigeons were trained to peck a key under a multiple fixed-ratio 25 fixed-ratio 175 schedule of food presentation. CP-135807 (0.1 mg/kg; i.m.; single dose) fully and dose-dependently substitutes for the training dose in adult male Carneau pigeons^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 151272-90-1
Masse moléculaire 351.40
Formule C₁₉H₂₁N₅O₂
SMILES

O=[N+](C1=CC=CN=C1NC2=CC3=C(NC=C3C[C@@H]4N(C)CCC4)C=C2)[O-]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mansbach RS, et al. CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology (Berl). 1996 Dec;128(3):313-9. [Content Brief]

[2]. Macor J E, et al. Use of 2, 5-Dimethylpyrrole as an Amino-Protecting Group in an Efficient Synthesis of 5-Amino-3-[(N-methyl-pyrrolidin-2 (R)-yl) methyl] indole[J]. The Journal of Organic Chemistry, 1994, 59(24): 7496-7498.

Calculators

Calculateur de molarité

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Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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