Flumezapine
Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research.
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- CAS No.: 61325-80-2
- Formule: C17H19FN4S
- Masse moléculaire:330.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 61325-80-2
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Masse moléculaire 330.42
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Formule C17H19FN4S
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SMILES
FC1=CC2=C(NC3=C(C(N4CCN(CC4)C)=N2)C=C(C)S3)C=C1
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Synonyms
LY 120363
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Fuller RW, Mason NR. Flumezapine, an antagonist of central dopamine and serotonin receptors. Res Commun Chem Pathol Pharmacol. 1986 Oct;54(1):23-34. [Content Brief]
[2]. Fuller RW, Snoddy HD. Flumezapine and zotepine: 5-hydroxytryptamine antagonism not involved in the lack of synergism of these antipsychotic drugs with amfonelic acid in rats. J Pharm Pharmacol. 1985 Oct;37(10):755-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Flumezapine Related Classifications
HY-106605 Related Classifications
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