HSN748
HSN748 is a Ponatinib (HY-12047) analogue and a multikinase inhibitor. HSN748 has inhibitory activity on FLT3, ABL1, RET, PDGFRα/β, MNK1, MNK2 and other kinases. HSN748 can inhibit the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines and can be used in the study of leukemia.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2409925-53-5
- Formule: C27H24F3N7O
- Masse moléculaire:519.52
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
PDGFRα |
PDGFRβ |
MNK1 |
MNK2 |
Chemical Information
-
CAS No. 2409925-53-5
-
Masse moléculaire 519.52
-
Formule C27H24F3N7O
-
SMILES
O=C(C1=CC(C#CC2=CN=C3C=CC=NN23)=CN=C1)NC4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)