Salviandulin E
Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL.
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- CAS No.: 158994-32-2
- Formule: C20H16O6
- Masse moléculaire:352.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Trypanosoma |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | IC50 |
0.84 μg/mL
Compound: 1
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Cytotoxicity against human MRC5 cells
Cytotoxicity against human MRC5 cells
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[PMID: 24388808] |
Salviandulin E shows cytotoxicity in MRC-5 cells with an IC50 value of 0.84 µg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 158994-32-2
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Masse moléculaire 352.34
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Formule C20H16O6
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SMILES
CC1=C2[C@@]3(C=CC4=C1[C@H](C5=COC=C5)OC4=O)C(C(OC3)=O)=C[C@@H](C2)O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Narukawa Y, et al. A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV. J Nat Med. 2006 Jul;60(3):206-209. [Content Brief]
[2]. Aoyagi Y, et al. Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorg Med Chem Lett. 2014 Jan 15;24(2):442-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Salviandulin E Related Classifications
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