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Cat. No.: HY-12308

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TCS 2314

Name: TCS 2314
Brand: MedChemExpress
SKU: HY-12308
Price: 350.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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TCS 2314 (compound 3) is orally active and selective very late antigen-4 (VLA-4, α4β1, CD49d/CD29) antagonist with an IC₅₀ of 4.4 nM.

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Pureté: 98.5%
CAS No.: 317353-73-4
Formule: C₂₈H₃₄N₄O₆
Masse moléculaire:522.59

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

TCS 2314 Chemical Structure

CAS No.: 317353-73-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

TCS 2314 (compound 3) is orally active and selective very late antigen-4 (VLA-4, α4β1, CD49d/CD29) antagonist with an IC₅₀ of 4.4 nM^[1].

IC₅₀ & Target

IC50: 4.4 nM (Very late antigen-4)^[1]

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Chemical Information

CAS No. 317353-73-4
Appearance Solid
Masse moléculaire 522.59
Formule C₂₈H₃₄N₄O₆
Color White to off-white
SMILES

O=C(O)CC1CCN(C([C@H]2N(C(CC3=CC=C(NC(NC4=CC=CC=C4C)=O)C=C3)=O)CCOC2)=O)CC1
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Muro F, et al. Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist. J Med Chem. 2009 Dec 24;52( [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Bioz

TCS 2314

Cyclo(-RGDfK)

CWHM-12

BIO5192

MK-0429

Cyclo(RGDyK) trifluoroacetate

Cilengitide TFA

Vedolizumab

RGD

Arg-Gly-Asp-Ser

Firategrast

Cilengitide

A-205804

Voir tous les produits spécifiques à Isoform Integrin

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TCS 2314 Related Classifications

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