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Cat. No.: HY-N17756

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Withanolide D

Withanolide D (Compound 2) is a steroidal ester found in Withania somnifera (L.) Dunal, with anticancer activity. Withanolide D can activate the heat-shock factor 1 (HSF1)-dependent stress response. Withanolide D can be used for the research of cancer such as lymphoma.

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CAS No.: 30655-48-2
Formule: C₂₇H₃₆O₆
Masse moléculaire:456.57

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Withanolide D Chemical Structure

CAS No.: 30655-48-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

HSF1

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In Vitro

Withanolide D exhibits cytotoxicity against various cancer cell lines and shows IC₅₀ values of 324 and 710 nM for CHP-100 and 293T cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 30655-48-2
Masse moléculaire 456.57
Formule C₂₇H₃₆O₆
SMILES

C[C@]12[C@@]3([C@H](C=CC2=O)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H]([C@@]6([H])CC(C)=C(C(O6)=O)C)O)C)([H])O3
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Hypogymnia vittata
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wijeratne EMK, et al. Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation. J Nat Prod. 2018 Apr 27;81(4):825-837. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Withanolide D

Voir tous les produits spécifiques à Isoform HSP

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Withanolide D Related Classifications

HY-N17756 Related Classifications