CYP1B1-IN-8
CYP1B1-IN-8 (Compound 14b) is a CYP1B1 inhibitor (IC50: 4.14 × 10–5 nM). CYP1B1-IN-8 reduces the resistance in A549 cells to Paclitaxel (HY-B0015), and inhibits cell migration and invasion.
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- CAS 番号: 3052218-49-9
- 分子式: C16H15ClIN3
- 分子量:411.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
11.13 nM
Compound: 14b
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Reversal of DMBA-stimulated PTX resistance in human A549 cells assessed as PTX IC50 for inhibition of cell viability at 10 uM incubated for 36 hrs in presence of DMBA and PTX by MTT assay (Rvb = 119 +/-2.62 nM)
Reversal of DMBA-stimulated PTX resistance in human A549 cells assessed as PTX IC50 for inhibition of cell viability at 10 uM incubated for 36 hrs in presence of DMBA and PTX by MTT assay (Rvb = 119 +/-2.62 nM)
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[PMID: 38509663] |
化学情報
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CAS 番号 3052218-49-9
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分子量 411.67
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分子式 C16H15ClIN3
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SMILES
IC1=CC=C(C2=NC3=CC=CC=C3C(NCC)=N2)C=C1.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CYP1B1-IN-8 関連分類
HY-161403 関連分類
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