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Cat. No.: HY-116708

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DCE_254

DCE_254 is an EZH2 inhibitor (IC₅₀=11 μM) that also exhibits significant antiproliferative activity against lymphoma cell lines. DCE_254 inhibits the development of hypermethylation-related cancers by inhibiting the SAM-mediated methyl transfer process (IC₅₀=10.3 μM).

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CAS No.: 673443-80-6
Formule: C₂₁H₁₇N₉OS
Masse moléculaire:443.48

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

DCE_254 Chemical Structure

CAS No.: 673443-80-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Histone Methyltransferase :

Chemical Information

CAS No. 673443-80-6
Masse moléculaire 443.48
Formule C₂₁H₁₇N₉OS
SMILES

O=C1N=C(NC(CSC2=NN=NN2C3=CC=CC=C3)=C1)NC4=NC(C)=C5C=CC=CC5=N4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wu Y, et al. Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays[J]. Bioorganic & Medicinal Chemistry Letters, 2016, 26(15): 3813-3817. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
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DCE_254

Voir tous les produits spécifiques à Isoform Histone Methyltransferase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DCE_254 Related Classifications

HY-116708 Related Classifications