4-Hydroxy MET
Based on 1 Customer Validation
4-Hydroxy MET (4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine psychoactive substance. 4-Hydroxy MET is a partial 5-HT2A receptor agonist, a serotonin transporter inhibitor and weak norepinephrine transporter inhibitor. 4-Hydroxy MET affects emotional, motoric, and cognitive functions via serotonergic hallucinogenic activity.
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- Reinheit: 99.30%
- CAS. Nr.: 77872-41-4
- Formel: C13H18N2O
- Molecular Weight:218.29
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Speicherung:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
4-Hydroxy MET (5-100 μM; 60-120 min) incubation of pooled human liver microsomes generates 12 distinct phase I metabolites, with mono-hydroxylation, dihydroxylation, demethylation, deethylation, carboxylic acid formation, and N-oxide formation as key biotransformation pathways[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 77872-41-4
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Appearance Solid
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Molecular Weight 218.29
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Formel C13H18N2O
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Color White to light blue
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SMILES
CN(CCC1=CNC2=C1C(O)=CC=C2)CC
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Synonyms
4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
DMSO : ≥ 100 mg/mL (458.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5811 mL | 22.9053 mL | 45.8106 mL | 114.5266 mL |
| 5 mM | 0.9162 mL | 4.5811 mL | 9.1621 mL | 22.9053 mL | |
| 10 mM | 0.4581 mL | 2.2905 mL | 4.5811 mL | 11.4527 mL | |
| 15 mM | 0.3054 mL | 1.5270 mL | 3.0540 mL | 7.6351 mL | |
| 20 mM | 0.2291 mL | 1.1453 mL | 2.2905 mL | 5.7263 mL | |
| 25 mM | 0.1832 mL | 0.9162 mL | 1.8324 mL | 4.5811 mL | |
| 30 mM | 0.1527 mL | 0.7635 mL | 1.5270 mL | 3.8176 mL | |
| 40 mM | 0.1145 mL | 0.5726 mL | 1.1453 mL | 2.8632 mL | |
| 50 mM | 0.0916 mL | 0.4581 mL | 0.9162 mL | 2.2905 mL | |
| 60 mM | 0.0764 mL | 0.3818 mL | 0.7635 mL | 1.9088 mL | |
| 80 mM | 0.0573 mL | 0.2863 mL | 0.5726 mL | 1.4316 mL | |
| 100 mM | 0.0458 mL | 0.2291 mL | 0.4581 mL | 1.1453 mL |
4-Hydroxy MET Related Classifications
Art. -Nr.: HY-118796
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- 4-Hydroxy MET
- 77872-41-4
- 4-HO-MET
- 4-Hydroxy-N-methyl-N-ethyltryptamine
- 5-HT Receptor
- Serotonin Transporter
- norepinephrine transporter
- human liver microsomes
- phase I metabolites
- dihydroxylation
- N-oxide formation
- deethylation
- 5-HT2A receptor
- demethylation
- serotonin transporter
- mono-hydroxylation
- Inhibitor
- inhibitor
- inhibit