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SCAND1 - SCAN domain containing 1 Gene

Also Known as RAZ1; SDP1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 51282

About SCAND1

Cytogenetic location: 20q11.23 Genomic coordinates (GRCh38): 20:35,953,624-35,959,472 (from NCBI)

This gene has 3 transcripts (splice variants), 322 orthologues and 29 paralogues. Ubiquitous expression in kidney (RPKM 14.6), fat (RPKM 13.5) and 25 other tissues.

Summary

This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

SCAND1 Products (3)

mRNA	Protein	Name
NM_001385710.1	NP_001372639.1	SCAN domain-containing protein 1
NM_016558.4	NP_057642.1	SCAN domain-containing protein 1
NM_033630.3	NP_361012.3	SCAN domain-containing protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Verweise	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SCAND1 Protein Structure

SCAN

0
100
179 a.a.

Protein Preferred Names	Protein Names
SCAN domain-containing protein 1	SCAN-related protein RAZ1

SCAND1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	SCAND1	P57086	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	KRT40	Homo sapiens	Q6A162	Validated Y2H	32296183
Intra	SCAND1	P57086	KRT40	Homo sapiens	Q6A162	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF483	Homo sapiens	Q6P088	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF483	Homo sapiens	Q6P088	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF483	Homo sapiens	Q6P088	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF394	Homo sapiens	Q53GI3	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF394	Homo sapiens	Q53GI3	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF394	Homo sapiens	Q53GI3	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF397	Homo sapiens	Q8NF99	Y2H Array	20211142
Intra	SCAND1	P57086	ZNF449	Homo sapiens	Q6P9G9	Validated Y2H	25416956
Intra	SCAND1	P57086	ZNF449	Homo sapiens	Q6P9G9	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF449	Homo sapiens	Q6P9G9	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF449	Homo sapiens	Q6P9G9	Y2H Array	25416956
Intra	SCAND1	P57086	ZNF449	Homo sapiens	Q6P9G9	Y2H Array	32296183
Intra	SCAND1	P57086	PGBD1	Homo sapiens	Q96JS3	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	PGBD1	Homo sapiens	Q96JS3	Y2H Array	32296183
Intra	SCAND1	P57086	PGBD1	Homo sapiens	Q96JS3	Validated Y2H	25416956
Intra	SCAND1	P57086	PGBD1	Homo sapiens	Q96JS3	Validated Y2H	32296183
Intra	SCAND1	P57086	PGBD1	Homo sapiens	Q96JS3	Y2H Array	31515488
Intra	SCAND1	P57086	RPRM	Homo sapiens	Q9NS64	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	RPRM	Homo sapiens	Q9NS64	Validated Y2H	32296183
Intra	SCAND1	P57086	RPRM	Homo sapiens	Q9NS64	Y2H Array	32296183
Intra	SCAND1	P57086	ZKSCAN7	Homo sapiens	Q9P0L1-2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZKSCAN7	Homo sapiens	Q9P0L1-2	Y2H Array	32296183
Intra	SCAND1	P57086	ZKSCAN7	Homo sapiens	Q9P0L1-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF174	Homo sapiens	Q15697-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF174	Homo sapiens	Q15697-2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF174	Homo sapiens	Q15697-2	Y2H Array	32296183
Intra	SCAND1	P57086	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	AGTRAP	Homo sapiens	Q6RW13-2	Validated Y2H	32296183
Intra	SCAND1	P57086	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF397	Homo sapiens	Q8NF99-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF397	Homo sapiens	Q8NF99-2	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF397	Homo sapiens	Q8NF99-2	MAPPIT	32296183
Intra	SCAND1	P57086	ZNF397	Homo sapiens	Q8NF99-2	Validated Y2H	32296183
Intra	SCAND1	P57086	TMEM239	Homo sapiens	Q8WW34-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TMEM239	Homo sapiens	Q8WW34-2	Validated Y2H	32296183
Intra	SCAND1	P57086	TMEM239	Homo sapiens	Q8WW34-2	Y2H Array	32296183
Intra	SCAND1	P57086	CCDC51	Homo sapiens	Q96ER9	Validated Y2H	32296183
Intra	SCAND1	P57086	CCDC51	Homo sapiens	Q96ER9	Y2H Array	32296183
Intra	SCAND1	P57086	CCDC51	Homo sapiens	Q96ER9	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN12	Homo sapiens	O43309	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF396	Homo sapiens	Q96N95-3	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF396	Homo sapiens	Q96N95-3	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF396	Homo sapiens	Q96N95-3	Y2H Array	32296183
Intra	SCAND1	P57086	NDUFB5	Homo sapiens	O43674	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	NDUFB5	Homo sapiens	O43674	Y2H Array	32296183
Intra	SCAND1	P57086	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	DGAT2L6	Homo sapiens	Q6ZPD8	Validated Y2H	32296183
Intra	SCAND1	P57086	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF213	Homo sapiens	O14771	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF213	Homo sapiens	O14771	Y2H Array	32296183
Intra	SCAND1	P57086	TMEM95	Homo sapiens	Q3KNT9	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TMEM95	Homo sapiens	Q3KNT9	Validated Y2H	32296183
Intra	SCAND1	P57086	TMEM95	Homo sapiens	Q3KNT9	Y2H Array	32296183
Intra	SCAND1	P57086	TVP23A	Homo sapiens	A6NH52	Y2H Array	32296183
Intra	SCAND1	P57086	TVP23A	Homo sapiens	A6NH52	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TMEM207	Homo sapiens	Q6UWW9	Validated Y2H	32296183
Intra	SCAND1	P57086	TMEM207	Homo sapiens	Q6UWW9	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TMEM207	Homo sapiens	Q6UWW9	Y2H Array	32296183
Intra	SCAND1	P57086	SHISA5	Homo sapiens	Q8N114-3	Validated Y2H	32296183
Intra	SCAND1	P57086	SHISA5	Homo sapiens	Q8N114-3	Y2H Array	32296183
Intra	SCAND1	P57086	SHISA5	Homo sapiens	Q8N114-3	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN25	Homo sapiens	Q6NSZ9-2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZSCAN25	Homo sapiens	Q6NSZ9-2	Y2H Array	32296183
Intra	SCAND1	P57086	ZSCAN25	Homo sapiens	Q6NSZ9-2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZKSCAN3	Homo sapiens	Q9BRR0	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZKSCAN3	Homo sapiens	Q9BRR0	Validated Y2H	32296183
Intra	SCAND1	P57086	ZKSCAN3	Homo sapiens	Q9BRR0	Y2H Array	32296183
Intra	SCAND1	P57086	RNF186	Homo sapiens	Q9NXI6	Y2H Array	32296183
Intra	SCAND1	P57086	RNF186	Homo sapiens	Q9NXI6	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	RNF186	Homo sapiens	Q9NXI6	Validated Y2H	32296183
Intra	SCAND1	P57086	APH1A	Homo sapiens	Q96BI3	Validated Y2H	32296183
Intra	SCAND1	P57086	APH1A	Homo sapiens	Q96BI3	Y2H Array	32296183
Intra	SCAND1	P57086	APH1A	Homo sapiens	Q96BI3	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZKSCAN4	Homo sapiens	Q969J2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZKSCAN4	Homo sapiens	Q969J2	Y2H Array	25416956
Intra	SCAND1	P57086	SFT2D1	Homo sapiens	Q8WV19	Y2H Array	32296183
Intra	SCAND1	P57086	SFT2D1	Homo sapiens	Q8WV19	Validated Y2H	32296183
Intra	SCAND1	P57086	SFT2D1	Homo sapiens	Q8WV19	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	LHX4	Homo sapiens	Q969G2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	LHX4	Homo sapiens	Q969G2	Validated Y2H	32296183
Intra	SCAND1	P57086	LHX4	Homo sapiens	Q969G2	Y2H Array	32296183
Intra	SCAND1	P57086	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	25416956
Intra	SCAND1	P57086	PNMA1	Homo sapiens	Q8ND90	Y2H Array	25416956
Intra	SCAND1	P57086	ZSCAN18	Homo sapiens	Q8TBC5	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN18	Homo sapiens	Q8TBC5	Validated Y2H	32296183
Intra	SCAND1	P57086	ZSCAN18	Homo sapiens	Q8TBC5	Y2H Array	32296183
Intra	SCAND1	P57086	SLC17A9	Homo sapiens	Q9BYT1	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	SLC17A9	Homo sapiens	Q9BYT1	Validated Y2H	32296183
Intra	SCAND1	P57086	SLC17A9	Homo sapiens	Q9BYT1	Y2H Array	32296183
Intra	SCAND1	P57086	ZSCAN23	Homo sapiens	Q3MJ62	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN23	Homo sapiens	Q3MJ62	Validated Y2H	32296183
Intra	SCAND1	P57086	ZSCAN23	Homo sapiens	Q3MJ62	Y2H Array	32296183
Intra	SCAND1	P57086	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	SCAND1	P57086	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF24	Homo sapiens	P17028	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF24	Homo sapiens	P17028	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	RER1	Homo sapiens	O15258	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	RER1	Homo sapiens	O15258	Y2H Array	32296183
Intra	SCAND1	P57086	ZSCAN16	Homo sapiens	Q9H4T2	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN16	Homo sapiens	Q9H4T2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZSCAN16	Homo sapiens	Q9H4T2	Y2H Array	32296183
Intra	SCAND1	P57086	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	25416956
Intra	SCAND1	P57086	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	32296183
Intra	SCAND1	P57086	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
Intra	SCAND1	P57086	CALCOCO2	Homo sapiens	Q13137	Validated Y2H	32296183
Intra	SCAND1	P57086	CALCOCO2	Homo sapiens	Q13137	Y2H Array	32296183
Intra	SCAND1	P57086	CALCOCO2	Homo sapiens	Q13137	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZSCAN32	Homo sapiens	Q9NX65	Y2H Array	20211142
Intra	SCAND1	P57086	ZNF446	Homo sapiens	Q9NWS9-2	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF165	Homo sapiens	P49910	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF165	Homo sapiens	P49910	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TRIP6	Homo sapiens	Q15654	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	TRIP6	Homo sapiens	Q15654	Y2H Array	32296183
Intra	SCAND1	P57086	TRIP6	Homo sapiens	Q15654	Validated Y2H	32296183
Intra	SCAND1	P57086	ZKSCAN7	Homo sapiens	Q9P0L1	Y2H Prey Pooling	25416956
Intra	SCAND1	P57086	ZKSCAN7	Homo sapiens	Q9P0L1	Y2H Pooling	16189514
Intra	SCAND1	P57086	ZNF496	Homo sapiens	Q96IT1	Validated Y2H	32296183
Intra	SCAND1	P57086	ZNF496	Homo sapiens	Q96IT1	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF496	Homo sapiens	Q96IT1	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	ZNF263	Homo sapiens	O14978	Y2H Array	32296183
Intra	SCAND1	P57086	ZNF263	Homo sapiens	O14978	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	SCAND1	P57086	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	SCAND1	P57086	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	SCAND1	P57086	POU2AF1	Homo sapiens	Q16633	Validated Y2H	32296183
Intra	SCAND1	P57086	POU2AF1	Homo sapiens	Q16633	Y2H Array	32296183
Intra	SCAND1	P57086	POU2AF1	Homo sapiens	Q16633	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Foodborne Botulism	Botulism Botulism Poisoning Intoxication With Clostridium Botulinum Toxin Wound Botulism Food Poisoning Due To Clostridium Botulinum Infection Due To Clostridium Botulinum Infant Botulism Intoxication Botulism Botulism, Infantile Clostridium Botulinum Poisoning Botulism Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS12483	SCAND1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SCAND1	VGNC	VGNC:57023
Macaca mulatta	SCAND1	VGNC	VGNC:81560
Rattus norvegicus	SCAND1	RGD	RGD:1308530
Mus musculus	SCAND1	MGD	MGI:1343132
Canis familiaris	SCAND1	VGNC	VGNC:54728
Others	SCAND1	NCBI