Cefcapene pivoxil
Cefcapene pivoxil, the pivalate ester prodrug form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene has the potential for the palmoplantar pustulosis (PPP) research.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Cefcapene pivoxil hydrochloride and Cefcapene pivoxil hydrochloride hydrate) usually boasts enhanced water solubility and stability.
For research use only. We do not sell to patients.
- CAS No.: 105889-45-0
- Formula: C23H29N5O8S2
- Molecular Weight:567.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Description
IC50 & Target
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β-lactam |
Chemical Information
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CAS No. 105889-45-0
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Molecular Weight 567.64
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Formula C23H29N5O8S2
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SMILES
CC(C)(C)C(OCOC(C1=C(COC(N)=O)CS[C@@]([C@@H]2NC(/C(C3=CSC(N)=N3)=C\CC)=O)([H])N1C2=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Murakami M, et al. Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.Dermatology. 2015;231(4):304-11. [Content Brief]
[2]. Koh Okamoto, et al. Poor penetration of cefcapene into aqueous humor after oral administration of cefcapene pivoxil to patients undergoing cataract surgery. J Infect Chemother. 2020 Feb;26(2):312-315. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)