hsa62
hsa62 is a dual inhibitor for SIRT1 and SIRT2, with IC50 of 1.3 and 5.5 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 780822-35-7
- Formula: C19H14N6O4S2
- Molecular Weight:454.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
|
SIRT1 1.3 μM (IC50) |
SIRT2 5.5 μM (IC50) |
SIRT3 43.6 μM (IC50) |
Chemical Information
-
CAS No. 780822-35-7
-
Molecular Weight 454.48
-
Formula C19H14N6O4S2
-
SMILES
O=C1NC2=CC=C(S(=O)(NC3=CC(SC4=NN=CN4)=C(C5=C3C=CC=C5)O)=O)C=C2N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)